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1

Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody

Kenneth A Foon, Xiao-Dong Yang, Louis M Weiner, Arie S Belldegrun, Robert A Figlin, Jeffrey Crawford, Eric K Rowinsky, Janice P Dutcher, Nicholas J Vogelzang, Jared Gollub, John A Thompson, Garry Schw

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

2

The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue: 1996

Seamus O'Reilly, Eric K. Rowinsky

Journal:

Critical Reviews in Oncology/Hematology

Year:

1996

Language:

english

File:

PDF, 2.91 MB

english, 1996

3

Characterisation of the cutaneous pathology in non-small cell lung cancer (NSCLC) patients treated with the EGFR tyrosine kinase inhibitor erlotinib

Emma Guttman-Yassky, Alain Mita, Maja De Jonge, Lesley Matthews, Sean McCarthy, Kenneth K. Iwata, Jaap Verweij, Eric K. Rowinsky, James G. Krueger

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 1.96 MB

english, 2010

4

Mammalian Target of Rapamycin: A New Molecular Target for Breast Cancer

Monica M. Mita, Alain Mita, Eric K. Rowinsky

Journal:

Clinical Breast Cancer

Year:

2003

Language:

english

File:

PDF, 534 KB

english, 2003

5

mTOR Inhibition for Cancer Therapy: Past, Present and Future ||

Mita, Monica, Mita, Alain, Rowinsky, Eric K.

Year:

2016

Language:

english

File:

PDF, 5.72 MB

english, 2016

6

mTOR Inhibition for Cancer Therapy: Past, Present and Future || mTOR, Aging, and Cancer: A Dangerous Link

Mita, Monica, Mita, Alain, Rowinsky, Eric K.

Year:

2016

Language:

english

File:

PDF, 322 KB

english, 2016

7

Activity of multitargeted antifolate (pemetrexed disodium, LY231514) in patients with advanced colorectal carcinoma : Results from a Phase II study

William John, Joel Picus, Charles D. Blanke, Jeffery W. Clark, Lawrence N. Schulman, Eric K. Rowinsky, Donald E. Thornton, Patrick J. Loehrer

Journal:

Year:

2000

Language:

english

File:

PDF, 80 KB

english, 2000

8

Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies

Dr. Vinay Chaudhry, Eric K. Rowinsky, Susan E. Sartorius, Ross C. Donehower, David R. Cornblath

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 711 KB

english, 1994

9

Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor α

Gaurav D. Shah, Nick Loizos, Hagop Youssoufian, Jonathan D. Schwartz, Eric K. Rowinsky

Journal:

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

10

Targeting FMS-related tyrosine kinase receptor 3 with the human immunoglobulin G1 monoclonal antibody IMC-EB10

Hagop Youssoufian, Eric K. Rowinsky, James Tonra, Yiwen Li

Journal:

Year:

2010

Language:

english

File:

PDF, 112 KB

english, 2010

11

Vascular endothelial growth factor receptor-1 in human cancer : Concise review and rationale for development of IMC-18F1 (Human antibody targeting vascular endothelial growth factor receptor-1)

Jonathan D. Schwartz, Eric K. Rowinsky, Hagop Youssoufian, Bronislaw Pytowski, Yan Wu

Journal:

Year:

2010

Language:

english

File:

PDF, 223 KB

english, 2010

12

Massive adrenal hemorrhage secondary to metastatic lung carcinoma

Eric K. Rowinsky, Richard J. Jones, Martin D. Abeloff

Journal:

Pediatric Blood & Cancer

Year:

1986

Language:

english

File:

PDF, 625 KB

english, 1986

13

Assessment of N-methylformamide (NMF) administered orally on a three times weekly schedule: a phase I study

Eric K. Rowinsky, Louise B. Grochow, Alexander Hantel, David S. Ettinger, Barbara L. Vito, Ross C. Donehower

Journal:

Investigational New Drugs

Year:

1989

Language:

english

File:

PDF, 717 KB

english, 1989

14

The distribution of systemically administered [3H]-paclitaxel in rats: a quantitative autoradiographic study

Glenn J. Lesser, Stuart A. Grossman, Susan Eller, Eric K. Rowinsky

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.89 MB

english, 1995

15

A phase II, pharmacokinetic, and biologic study of semaxanib and thalidomide in patients with metastatic melanoma

Monica M. Mita, Eric K. Rowinsky, Leonardo Forero, S. Gail Eckhart, Elzbieta Izbicka, Geoffrey R. Weiss, Muralidhar Beeram, Alain C. Mita, Johann S. de Bono, Anthony W. Tolcher, Lisa A. Hammond, Paul

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 353 KB

english, 2007

16

Erlotinib plus gemcitabine in patients with unresectable pancreatic cancer and other solid tumors: phase IB trial

Tomislav Dragovich, Mark Huberman, Daniel D. Von Hoff, Eric K. Rowinsky, Paul Nadler, Debra Wood, Marta Hamilton, George Hage, Julie Wolf, Amita Patnaik

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 310 KB

english, 2007

17

Phase I study of paclitaxel poliglumex administered weekly for patients with advanced solid malignancies

Monica Mita, Alain Mita, John Sarantopoulos, Chris H. Takimoto, Eric K. Rowinsky, Ofelia Romero, Patrizia Angiuli, Cecilia Allievi, Amy Eisenfeld, Claire F. Verschraegen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 404 KB

english, 2009

18

Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28

Chia-Chi Lin, Muralidhar Beeram, Eric K. Rowinsky, Chris H. Takimoto, Chee M. Ng, Charles E. Geyer, Louis J. Denis, Johann S. De Bono, Desiree Hao, Anthony W. Tolcher, Sun-Young Rha, Jacques Jolivet,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 444 KB

english, 2009

19

The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer

Heather A. Wakelee, Chris H. Takimoto, Arturo Lopez-Anaya, Quincy Chu, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Eric K. Rowinsky, Desiree Hao, Petr Zatloukal, Charlotte D. Jacobs,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 393 KB

english, 2012

20

A phase I pharmacokinetic study of bexarotene with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer (NSCLC)

Jordi Rodon, Charlotte D. Jacobs, Quincy Chu, Eric K. Rowinsky, Arturo Lopez-Anaya, Chris H. Takimoto, Heather A. Wakelee

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 277 KB

english, 2012

21

Activity of the multitargeted antifolate LY231514 in the human tumor cloning assay

Carolyn D. Britten, Elzbieta Izbicka, Susan Hilsenbeck, Richard Lawrence, Karen Davidson, Caeser Cerna, Lionel Gomez, Eric K. Rowinsky, Steven Weitman, Daniel D. Von Hoff

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 110 KB

english, 1999

22

Bioavailablility of penclomedine and systemic exposure to 4-O-demethylpenclomedine in patients receiving oral and intravenous penclomedine

Seamus O'Reilly, Neil R. Hartman, Katherine M. Bowling, Eric K. Rowinsky, Ross C. Donehower, Jerry Collins, John M. Strong

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

23

Acute retinal toxicity from the novel anti-tumor agent, Irofulven

Robert Melendez, Joseph Harrison, Eric Rowinsky, Lisa Hammond, Thomas Fitzsimmons

Journal:

Documenta Ophthalmologica

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

24

A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas

Quincy S. C. Chu, Bahram Forouzesh, Samira Syed, Monica Mita, Garry Schwartz, Joshua Copper, Janet Curtright, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 362 KB

english, 2007

25

A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomes

Quincy S. C. Chu, Bahram Forouzesh, Samira Syed, Monica Mita, Garry Schwartz, Joshua Cooper, Janet Curtright, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

26

Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer

Jan C. Buckner, Bahram Forouzesh, Charles Erlichman, Manuel Hidalgo, Joseph P. Boni, Gary Dukart, Anna Berkenblit, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

27

A phase II, multicenter study of cetuximab monotherapy in patients with refractory, metastatic colorectal carcinoma with absent epidermal growth factor receptor immunostaining

Rafal Wierzbicki, Derek J. Jonker, Malcolm J. Moore, Scott R. Berry, Patrick J. Loehrer, Hagop Youssoufian, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 323 KB

english, 2011

28

Efficacy and safety of sorafenib in a subset of patients with advanced soft tissue sarcoma from a Phase II randomized discontinuation trial

Simon Pacey, Mark J. Ratain, Keith T. Flaherty, Stanley B. Kaye, Lisa Cupit, Eric K. Rowinsky, Chenghua Xia, Peter J. O’Dwyer, I. R. Judson

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 208 KB

english, 2011

29

A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction

Juan W. Valle, Anne Armstrong, Chris Newman, Valery Alakhov, Grzegorz Pietrzynski, Julie Brewer, Sue Campbell, Pippa Corrie, Eric K. Rowinsky, Malcolm Ranson

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 197 KB

english, 2011

30

Targeting the target of rapamycin (TOR): looking to mother nature

Eric K. Rowinsky

Journal:

Targeted Oncology

Year:

2011

Language:

english

File:

PDF, 98 KB

english, 2011

31

Approaches to optimize the use of monoclonal antibodies to epidermal growth factor receptor

Emiliano Calvo, Eric K. Rowinsky

Journal:

Current Oncology Reports

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

32

Clinical experience with monoclonal antibodies to epidermal growth factor receptor

Emiliano Calvo, Eric K. Rowinsky

Journal:

Current Oncology Reports

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

33

Pilot Trial of Alternating Paclitaxel and Doxorubicin in Advanced Breast Cancer

Worta J. McCaskill-Stevens, Joseph A. Sparano, Melody Cobleigh, Nicholas J. Robert, Carla Baughman, Donna Neuberg, Eric K. Rowinsky, George W. Sledge Jr.

Journal:

The Breast Journal

Year:

1997

Language:

english

File:

PDF, 613 KB

english, 1997

34

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

Hidalgo, Manuel, Rowinsky, Eric K

Journal:

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

35

Phase I study of paclitaxel on a 3-hour schedule followed by carboplatin in untreated patients with stage IV non-small cell lung cancer

Eric K. Rowinsky, William A. Flood, Susan E. Sartorius, Kathy M. Bowling, David S. Ettinger

Journal:

Investigational New Drugs

Year:

1997

Language:

english

File:

PDF, 61 KB

english, 1997

36

Activity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units

Lillian L. Siu, Daniel D. Von Hoff, Ada Rephaeli, Elzbieta Izbicka, Cesario Cerna, Lionel Gomez, Eric K. Rowinsky, S. Gail Eckhardt

Journal:

Investigational New Drugs

Year:

1998

Language:

english

File:

PDF, 63 KB

english, 1998

37

Phase II Study of 4-Ipomeanol, a Naturally Occurring Alkylating Furan, in Patients with Advanced Hepatocellular Carcinoma

Shailendra Lakhanpal, Ross C. Donehower, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

38

A Phase I and Pharmacologic Study of Pyrazoloacridine and Cisplatin in Patients with Advanced Cancer

E. Claire Dees, Eric K. Rowinsky, Dennis A. Noe, Seamus O'Reilly, Alex A. Adjei, Kathy Elza-Brown, Ross C. Donehower

Journal:

Investigational New Drugs

Year:

2003

Language:

english

File:

PDF, 109 KB

english, 2003

39

A Phase II Study of Intravenous Exatecan Mesylate (DX-8951f) Administered Daily for Five Days Every Three Weeks to Patients with Metastatic Adenocarcinoma of the Colon or Rectum

Melanie E. Royce, Eric K. Rowinsky, Paulo M. Hoff, John Coyle, Robert DeJager, Richard Pazdur, Leonard B. Saltz

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 99 KB

english, 2004

40

A phase I and pharmacokinetic study of the nonpolyglutamatable thymidylate synthase inhibitor ZD9331 plus docetaxel in patients with advanced solid malignancies

Garry H. Schwartz, Christopher B. Jones, Mitchell Garrison, Amita Patnaik, Chris Takimoto, Heather McCreery, Michael Skinner, Anthony W. Tolcher, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

41

Sequence-dependent cytotoxic effects due to combinations of cisplatin and the antimicrotubule agents taxol and vincristine

Eric K. Rowinsky, Martin J. Citardi, Dennis A. Noe, Ross C. Donehower

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1993

Language:

english

File:

PDF, 809 KB

english, 1993

42

A phase II randomized study of cetuximab and bevacizumab alone or in combination with gemcitabine as first-line therapy for metastatic pancreatic adenocarcinoma

Andrew H. Ko, Hagop Youssoufian, Jayne Gurtler, Karel Dicke, Omar Kayaleh, Heinz-Josef Lenz, Mark Keaton, Terry Katz, Shaila Ballal, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

43

Pharmacokinetic profiles of doxorubicin in combination with taxanes

Frankie Ann Holmes, Eric Keith Rowinsky

Journal:

Seminars in Oncology

Year:

2001

Language:

english

File:

PDF, 811 KB

english, 2001

44

Farnesyltransferase inhibitors and their potential in the treatment of breast carcinoma

Johann S de Bono, Anthony W Tolcher, Eric K Rowinsky

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 840 KB

english, 2003

45

A widening prospect: imatinib and novel applications of targeted therapy

Eric K Rowinsky

Journal:

Seminars in Oncology

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

46

Novel Agents That Target Tublin and Related Elements

Eric K. Rowinsky, Emiliano Calvo

Journal:

Seminars in Oncology

Year:

2006

Language:

english

File:

PDF, 263 KB

english, 2006

47

Paclitaxel (Taxol)

Wood, Alastair J.J., Rowinsky, Eric K., Donehower, Ross C.

Journal:

Boston Medical and Surgical Journal

Year:

1995

Language:

english

File:

PDF, 172 KB

english, 1995

48

Erosion of the principal investigator role in a climate of industry dominance

Eric K. Rowinsky

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 82 KB

english, 2005

49

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

James A Bonner, Paul M Harari, Jordi Giralt, Roger B Cohen, Christopher U Jones, Ranjan K Sur, David Raben, Jose Baselga, Sharon A Spencer, Junming Zhu, Hagop Youssoufian, Eric K Rowinsky, K Kian Ang

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 193 KB

english, 2010

50

The ErbB receptor family: a therapeutic target for cancer

Johann S. de Bono, Eric K. Rowinsky

Journal:

Trends in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 62 KB

english, 2002